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Importantly, enhanced neuroplasticity through BDNF upregulation represents a critical defense against age-related neurovascular dysfunction and glymphatic impairment, which contribute significantly to cognitive decline and neurodegenerative processes (Mansour et al., 2025)

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82,83 Oxidative Stress Oxidative stress is an imbalance between antioxidant capacity and free radicals, favoring free radicals and leading to molecular, cellular, and tissue damage

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